On March 30, 2010, White appeared on The Mo'Nique Show to promote his film Why Did I Get Married Too. White wrote the scripts for both Black Dynamite and his upcoming 3 Bullets in which he stars with Bokeem Woodbine. He also starred in the film Blood and Bone and the blaxploitation homage Black Dynamite, both released in 2009. White played the role of the mob boss Gambol in the 2008 film The Dark Knight. His film Why Did I Get Married? opened at number one at the box office on October 12, 2007.

He appeared in Kill Bill: Volume 2, although his role was cut from the theatrical release. He also appears in Michelle Yeoh's Silver Hawk in 2004. White showcases his martial arts skills in the direct-to-DVD film Undisputed II: Last Man Standing. Since 2003, in addition to his on screen roles, White has been doing voice work, including in Static Shock and Justice League. In 2003, he starred in Busta Rhymes and Mariah Carey's music video ' I Know What You Want'.

In 2001, he also starred opposite fellow martial artist Steven Seagal in Exit Wounds. A few years earlier, he acted in Full Contact, with Jerry Trimble. White starred opposite Jean-Claude Van Damme in Universal Soldier: The Return, in 1999. His work in Spawn earned him a nomination for the Blockbuster Entertainment Award. He portrayed the eponymous character in the 1997 movie Spawn, making him the first African American to portray a major comic book superhero in a major motion picture. White's first major starring role and breakout performance was in the 1995 HBO film Tyson, as heavyweight boxer Mike Tyson. He cites his history in education as the reason why, despite his personal love for the music genre on 'a lot of levels', he cannot 'in good ' have a positive opinion on hip hop or 'excuse some of pervasive and destructive elements', mainly due to his experience with youngsters who had difficulty seeing the difference between it and real life. White is a former special education teacher and taught students with behavioral problems for three years. He next took up Shōtōkan and moved on to other styles later. White started training in the martial arts at the age of four in Jujutsu. White is a martial artist in nine different styles: Shōtōkan, Goju-Ryu (for which he studied under Master Eddie Morales where he learned to sharpen his Goju karate technique), Taekwondo, Kobudō, Tang Soo Do, Wushu, Brazilian Jiu-Jitsu, Kyokushin and boxing, with a specific focus in Kyokushin Karate (although his style incorporates aspects of many different martial arts forms).

Never back down tattoo